I see. So you’re using the 1.6.0 Ledger Nano S firmware and the 2.0.3 Cardano app for Ledger, these are both the latest version right now, so that’s good. Also, you’re trying to send to an address that starts with
addr1..., that’s also good.
What I don’t exactly understand is, what app are you using to interact with the Ledger device? Since it’s a hardware wallet, I recommend trying https://adalite.io/, since it’s compatible with Shelley and the Ledger Nano S device. Yoroi and Daedalus aren’t all the way there at the moment.
Steps 1-12 from this AdaLite guide explain how to convert your Ledger ADA balance into to Shelley-compatible, then you can send ADA in AdaLite from the Sending tab like this.
I definitely don’t recommend entering your Ledger mnemonic into Daedalus, you’d have to reset the device, create a new phrase, and transfer everything to new addresses to make the hardware wallet secure again.