Sure you can. If you use AWS you might as well use an arm64 image from them. They have CentOS8 on arm64 for example. In that way you can build docker images on AWS that will then run on your Pi as well.
Unfortunately, the upstream Nix build does currently not work on arm64 because of [BUG] - cardano-node build fails with “Segmentation fault” on aarch64
For the nessusio/cardano images I have a convoluted workaround that builds the arm64 derivation through Docker (instead of Nix). Once I have the the binaries for the node & cli a normal Nix build can continue.
If you like this work, you may want to endorse this [CIP] - Provide high quality multiarch docker image and k8s support. The PRs that I have so far are here