I would use new keys.
That will change the keyhash in the policy.script JSON. Additionally, you will probably want a different value for before, which also changes the policy.script.
If the policy.script changes, the policy id also changes. And this other policy id has to be changed in the metadata.json and in the cardano-cli transaction build command also.
The --tx-ins and --tx-outs will be totally different, anyway.